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Domantis can format Domain Antibody™ leads as Dual Targeting dAbs™ to bind to two therapeutic targets. The Dual Targeting formats include: IgG-like molecules; PEGylated fusion proteins; and Anti-serum albumin fusion proteins. In the IgG-like Dual Targeting format, two variable domains (red and green) bind to two therapeutic targets on each arm of the Dual Targeting IgG. |